Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | PDE6D | O43924 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDE6A | P16499 | 2/20 | 0.36 |
| ▸ | PDE6G | P18545 | 2/20 | 0.36 |
| ▸ | PDE6B | P35913 | 2/20 | 0.36 |
| ▸ | PDE6C | P51160 | 2/20 | 0.36 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12061561 | 1.00 | SLC6A4 (0.43) | SLC6A4CHRM1CYP2D6CYP2C9ADRA1D | |
| SCHEMBL14077 | 0.95 | SLC6A4 (0.47) | SLC6A4CHRM1CYP2D6CYP2C9ADRA1D | |
| SCHEMBL14035 | 0.92 | SLC6A4 (0.39) | SLC6A4CA5AMEN1KMT2APARP1 | |
| SCHEMBL12062415 | 0.91 | CHRM1 (0.48) | CHRM1CYP2D6CYP2C9PDE6DPDE5A | |
| SCHEMBL14551 | 0.88 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| SCHEMBL13698 | 0.87 | DRD2 (0.37) | SLC6A4CHRM1CYP2D6 | |
| SCHEMBL14463 | 0.82 | DRD2 (0.44) | — | |
| SCHEMBL14539 | 0.79 | ADRA2C (0.36) | MEN1KMT2A | |
| SCHEMBL14574 | 0.76 | DRD2 (0.36) | — | |
| SCHEMBL7550 | 0.75 | PDE5A (0.34) | CYP2C9ADRA1DADRA1AADRA1BCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031893-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031893-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | SLC6A4 4116/4885CHRM1 4701/4885CYP2D6 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.