Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463 | 0.90 | DRD2 (0.44) | DRD2DRD3FAAHADRA2CCAMK2D | |
| SCHEMBL14539 | 0.90 | ADRA2C (0.36) | DRD2DRD3FAAHADRA2CCAMK2D | |
| SCHEMBL13698 | 0.79 | DRD2 (0.37) | DRD2DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8076 | 0.79 | DRD2 (0.37) | DRD2DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12062415 | 0.77 | CHRM1 (0.48) | DRD2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12061561 | 0.76 | SLC6A4 (0.43) | — | |
| SCHEMBL14551 | 0.73 | ADRA1D (0.52) | DRD2DRD3ALDH1A1SIGMAR1 | |
| SCHEMBL14077 | 0.72 | SLC6A4 (0.47) | DRD2DRD3 | |
| SCHEMBL7550 | 0.64 | PDE5A (0.34) | KDM4EALDH1A1HSD17B10SIGMAR1 | |
| SCHEMBL991815 | 0.64 | TDP1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |