Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109772 | 0.79 | USP30 (0.43) | PDE4BTHRBALDH1A1TSHRMAPT | |
| SCHEMBL9109767 | 0.79 | USP30 (0.43) | PDE4BTHRBALDH1A1TSHRMAPT | |
| SCHEMBL13110285 | 0.78 | OGA (0.34) | GAAOGAALDH1A1HTTKDM4E | |
| SCHEMBL13110288 | 0.77 | MAPT (0.37) | OGAALDH1A1HTTKDM4ECYP2C19 | |
| SCHEMBL9205820 | 0.73 | MEN1 (0.46) | L3MBTL1GAAALDH1A1HTTTSHR | |
| SCHEMBL14539583 | 0.73 | PSEN1 (0.51) | ALDH1A1HTT | |
| SCHEMBL5656187 | 0.73 | PSEN1 (0.55) | ALDH1A1SMYD3SMN1; SMN2 | |
| SCHEMBL13110287 | 0.72 | MAPT (0.38) | OGAALDH1A1CYP2C19MAPT | |
| SCHEMBL5022945 | 0.72 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DTHRB | |
| SCHEMBL17469082 | 0.72 | CYP2C9 (0.35) | ALDH1A1TSHRCYP2C19POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214813-B2 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |