Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455355 | 0.95 | CACNA2D1 (0.38) | CACNA2D1TDP1LMNAPOLBALDH1A1 | |
| SCHEMBL1454309 | 0.90 | TDP1 (0.41) | CACNA2D1TDP1LMNAPOLBALDH1A1 | |
| SCHEMBL1454257 | 0.85 | ALDH1A1 (0.36) | CACNA2D1TDP1POLBALDH1A1CYP3A4 | |
| SCHEMBL8436767 | 0.82 | ALDH1A1 (0.45) | CACNA2D1TDP1LMNAPOLBALDH1A1 | |
| SCHEMBL11045235 | 0.81 | TDP1 (0.42) | CACNA2D1TDP1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1454763 | 0.79 | ALDH1A1 (0.46) | CACNA2D1TDP1LMNAALDH1A1CYP3A4 | |
| SCHEMBL30464709 | 0.79 | HDAC8 (0.43) | CACNA2D1TDP1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11533028 | 0.79 | HDAC8 (0.43) | CACNA2D1TDP1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20655979 | 0.79 | HDAC8 (0.43) | CACNA2D1TDP1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29745004 | 0.79 | HDAC8 (0.43) | CACNA2D1TDP1ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| CN-1921847-B | Amino alcohol compound | SANKYO CO | 2010-06-16 | — | — | CN | disclosed |
| US-20070191468-A1 | Amino alcohol compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-08-16 | — | — | US | disclosed |
| CN-1921847-A | Amino alcohol compound | SANKYO CO (JP) | 2007-02-28 | — | — | CN | disclosed |
| EP-1733724-A1 | AMINO ALCOHOL COMPOUND | Sankyo Company, Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191468-A1 | Amino alcohol compound | ADH1A, ADH1C, BCAT1 | CACNA2D1 3385/4885TDP1 1914/4885LMNA 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.