Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ODC1 | P11926 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482234 | 0.89 | COXFA4 (0.49) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL16865499 | 0.84 | COXFA4 (0.48) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL30874660 | 0.82 | COXFA4 (0.53) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL8066269 | 0.82 | COXFA4 (0.53) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL6648245 | 0.82 | ALDH1A1 (0.57) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL30140565 | 0.81 | XDH (0.68) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL8723354 | 0.81 | XDH (0.68) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL16694172 | 0.81 | COXFA4 (0.59) | COXFA4ALDH1A1CYP3A4HIF1AEPAS1 | |
| SCHEMBL11398330 | 0.78 | COXFA4 (0.62) | COXFA4PTPN1HPGDALDH1A1TDP1 | |
| SCHEMBL7766618 | 0.77 | COXFA4 (0.49) | COXFA4PTPN1HPGDALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |