Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150093 | 0.86 | KMT2A (0.39) | KMT2AMEN1TRPA1CYP3A4CYP2C9 | |
| SCHEMBL4150636 | 0.84 | KMT2A (0.36) | KMT2AMEN1TRPA1CYP3A4CYP2C9 | |
| SCHEMBL4908707 | 0.78 | IL2 (0.44) | TRPA1RORCCYP1A2TLR7 | |
| SCHEMBL13774583 | 0.78 | RAB9A (0.36) | KMT2AMEN1TRPA1RORCCYP1A2 | |
| SCHEMBL4913867 | 0.77 | MAPT (0.42) | KMT2AMEN1TRPA1USP2MAPT | |
| SCHEMBL4142017 | 0.77 | TRPA1 (0.33) | KMT2AMEN1TRPA1USP2MAPT | |
| SCHEMBL14546320 | 0.77 | ATM (0.49) | KMT2AMEN1TRPA1USP2MAPT | |
| SCHEMBL13774520 | 0.77 | MEN1 (0.41) | KMT2AMEN1TRPA1RORCRAB9A | |
| SCHEMBL4145038 | 0.77 | ATM (0.35) | KMT2AMEN1TRPA1USP2MAPT | |
| SCHEMBL4148243 | 0.76 | RORC (0.35) | KMT2AMEN1TRPA1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |