Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.37 |
| ▸ | CD40 | P25942 | 1/20 | 0.37 |
| ▸ | CD40LG | P29965 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546744 | 0.94 | P2RX5 (0.38) | THRBATICRPS6KA3ENPP2P2RX5 | |
| SCHEMBL14546741 | 0.93 | THRB (0.45) | THRBATICRPS6KA3ENPP2P2RX5 | |
| SCHEMBL14546921 | 0.89 | NSD2 (0.37) | THRBATICP2RX5P2RX4P2RX2 | |
| SCHEMBL14547026 | 0.88 | THRB (0.43) | THRBATICENPP2P2RX5P2RX4 | |
| SCHEMBL14546920 | 0.88 | THRB (0.41) | THRBATICRPS6KA3ENPP2P2RX2 | |
| SCHEMBL14546748 | 0.87 | TP53 (0.40) | THRBENPP2P2RX5P2RX4P2RX2 | |
| SCHEMBL14547012 | 0.87 | ENPP2 (0.42) | THRBATICRPS6KA3ENPP2P2RX5 | |
| SCHEMBL14546914 | 0.86 | THRB (0.44) | THRBATICENPP2P2RX5P2RX4 | |
| SCHEMBL14546784 | 0.86 | THRB (0.48) | THRBENPP2CD40CD40LGCYP2C19 | |
| SCHEMBL14546752 | 0.86 | THRB (0.48) | THRBENPP2CD40CD40LGCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |