Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592580 | 0.80 | RAB9A (0.63) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL27854840 | 0.75 | MEN1 (0.71) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL4065880 | 0.73 | MEN1 (0.70) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL1143297 | 0.73 | MEN1 (0.70) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL5505167 | 0.73 | MEN1 (1.00) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL136847 | 0.73 | MEN1 (0.70) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL1424722 | 0.73 | ALDH1A1 (1.00) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL12460895 | 0.71 | MEN1 (0.66) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL8649376 | 0.70 | MAPT (0.38) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL1365078 | 0.70 | RAB9A (0.72) | MEN1KMT2ARAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036730-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |