Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.65 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601802 | 0.93 | IAPP (0.65) | IAPPALOX5OR51E2APPCYP19A1 | |
| SCHEMBL28165571 | 0.92 | IAPP (0.82) | IAPPALOX5OR51E2APPCYP19A1 | |
| SCHEMBL9360095 | 0.91 | IAPP (0.87) | IAPPALOX5OR51E2APPCYP19A1 | |
| SCHEMBL28349297 | 0.91 | IAPP (0.84) | IAPPALOX5OR51E2APPCYP19A1 | |
| SCHEMBL31135939 | 0.87 | IAPP (0.80) | IAPPALOX5OR51E2ALOX15KDM4E | |
| SCHEMBL10307533 | 0.86 | ALOX5 (0.91) | IAPPALOX5OR51E2ALOX15LMNA | |
| SCHEMBL10307534 | 0.86 | ALOX5 (0.76) | IAPPALOX5OR51E2CYP19A1LMNA | |
| SCHEMBL21203290 | 0.85 | IAPP (0.72) | IAPPALOX5APPCYP19A1TYR | |
| SCHEMBL12659724 | 0.83 | IAPP (0.76) | IAPPALOX5APPCYP19A1TYR | |
| SCHEMBL10826044 | 0.83 | IAPP (1.00) | IAPPAPPCYP19A1TYRCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875426-B2 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | L'OREAL (FR) | 2005-04-05 | — | — | US | claimed |
| US-6872401-B2 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | L'OREAL (FR) | 2005-03-29 | — | — | US | claimed |
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | SOCIETE L'OREAL S.A. (FR) | 2004-01-15 | — | — | US | claimed |
| US-20030228268-A1 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | SOCIETE L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | claimed |
| EP-1348424-A1 | Self-tanning composition containing a tetrahydrocurcumine derivative and a self-tanning agent | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
| EP-1348418-A1 | Cosmetical or dermatological composition containing a tetrahydrocurcumin derivative and an oil bearing an amide group | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
| EP-3763419-A1 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | Anji Pharma (US) LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-2661266-B1 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ANJI PHARMA (US) LLC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10610500-B2 | Chemosensory receptor ligand-based therapies | ANJI PHARMA (US) LLC (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190038576-A1 | Chemosensory Receptor Ligand-Based Therapies | ANJI PHARMACEUTICALS INC. | 2019-02-07 | — | — | US | disclosed |
| EP-2978767-B1 | DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME | OREAL (FR) | 2018-10-03 | — | — | EP | disclosed |
| US-9962344-B2 | Chemosensory receptor ligand-based therapies | ELCELYX THERAPEUTICS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-9962344-B2 | Chemosensory receptor ligand-based therapies | ELCELYX THERAPEUTICS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20100168248-A1 | PROCESS FOR PRODUCING ENRICHED FRACTIONS OF TETRAHYDROXYCURCUMIN AND TETRAHYDROTETRAHDROXY-CURCUMIN FROM THE EXTRACTS OF CURCUMA LONGA | LAILA IMPEX (IN) | 2010-07-01 | — | — | US | disclosed |
| WO-2010004579-A2 | ORALLY ACTIVE CURCUMINOID COMPOUNDS | LAILA PHARMACEUTICALS PVT. LTD. (IN) | 2010-01-14 | — | — | WO | disclosed |
| US-6872401-B2 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | L'OREAL (FR) | 2005-03-29 | — | — | US | disclosed |
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | SOCIETE L'OREAL S.A. (FR) | 2004-01-15 | — | — | US | disclosed |
| US-20030228268-A1 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | SOCIETE L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | disclosed |
| EP-1348424-A1 | Self-tanning composition containing a tetrahydrocurcumine derivative and a self-tanning agent | L'OREAL (FR) | 2003-10-01 | — | — | EP | disclosed |
| EP-1348418-A1 | Cosmetical or dermatological composition containing a tetrahydrocurcumin derivative and an oil bearing an amide group | L'OREAL (FR) | 2003-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10610500-B2 | Chemosensory receptor ligand-based therapies | TAS1R2, TAS2R1, GPR119 | IAPP 145/4885ALOX5 2867/4885OR51E2 130/4885 |
| US-20100168248-A1 | PROCESS FOR PRODUCING ENRICHED FRACTIONS OF TETRAHYDROXYCURCUMIN AND TETRAHYDROTETRAHDROXY-CURCUMIN FROM THE EXTRACTS OF CURCUMA LONGA | HMOX1, HMOX2, HPD | IAPP 4028/4885ALOX5 305/4885OR51E2 985/4885 |
| US-20030228268-A1 | Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent | TYR, TES, TERT | IAPP 4766/4885ALOX5 963/4885OR51E2 3141/4885 |
| US-20190038576-A1 | Chemosensory Receptor Ligand-Based Therapies | TAS1R2, TAS2R1, GPR119 | IAPP 145/4885ALOX5 2867/4885OR51E2 130/4885 |
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | KRT18, DHCR24, FABP4 | IAPP 4863/4885ALOX5 39/4885OR51E2 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.