Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 3/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16067308 | 0.77 | TYR (0.61) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL28877689 | 0.76 | TYR (0.56) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL12261582 | 0.76 | LMNA (0.59) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| Bisdemethoxycurcumin SCHEMBL2574140 | 0.76 | AKR1B1 (1.00) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL11773809 | 0.76 | LMNA (0.59) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL15866315 | 0.75 | CA12 (0.44) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL12453517 | 0.74 | F3 (0.59) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL21281461 | 0.74 | ACHE (0.45) | MAOBCYP2C9CA1MMP1MMP2 | |
| SCHEMBL6266989 | 0.72 | APP (0.74) | AKR1B10AKR1B1MAOBPTGS2TYR | |
| SCHEMBL6266983 | 0.72 | APP (0.74) | AKR1B10AKR1B1MAOBPTGS2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007043058-A1 | PROCESS FOR PRODUCING ENRICHED FRACTIONS OF TETRAHYDROXYCURCUMIN AND TETRAHYDROTETRAHYDROXY-CURCUMIN FROM THE EXTRACTS OF CURCUMA LONGA | GOKARAJU GANGA RAJU (IN) | 2007-04-19 | — | — | WO | disclosed |