⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13772646 | 0.94 | MGAM (0.33) | — | |
| SCHEMBL12956510 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL2544830 | 0.89 | ACHE (0.31) | — | |
| SCHEMBL2554064 | 0.89 | ALDH1A1 (0.30) | — | |
| SCHEMBL14641834 | 0.88 | ALOX15 (0.32) | — | |
| SCHEMBL14548939 | 0.86 | MAPT (0.36) | — | |
| SCHEMBL12103158 | 0.86 | MEN1 (0.32) | — | |
| SCHEMBL14548935 | 0.85 | L3MBTL1 (0.36) | — | |
| SCHEMBL14548934 | 0.85 | — | — | |
| SCHEMBL14548945 | 0.84 | HDAC3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357723-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-22 | — | — | US | disclosed |
| US-8354455-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-15 | — | — | US | disclosed |
| US-8349901-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-08 | — | — | US | disclosed |