Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PDXK | O00764 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577071 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11457157 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1545975 | 0.77 | PDXK (0.53) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11460133 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL8904107 | 0.76 | PDXK (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11459772 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL12974505 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11459258 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11460033 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11450075 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710067-B2 | Method for the treatment, alleviation of symptoms of, relieving, improving and preventing a cognitive disease, disorder or condition | ALCOBRA LTD. (IL) | 2014-04-29 | — | — | US | disclosed |
| US-20130012549-A1 | Method for the Treatment, Alleviation of Symptoms of, Relieving, Improving and Preventing a Cognitive Disease, Disorder or Condition | ALCOBRA LTD. (IL) | 2013-01-10 | — | — | US | disclosed |
| US-20110294859-A1 | SUBSTITUTED PYRIDOXINE-LACTAM CARBOXYLATE SALTS | ALCOBRA LTD. (IL) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012549-A1 | Method for the Treatment, Alleviation of Symptoms of, Relieving, Improving and Preventing a Cognitive Disease, Disorder or Condition | ACHE, BCHE, GRIK5 | KDM4E 1328/4885ALDH1A1 886/4885HPGD 131/4885 |
| US-20110294859-A1 | SUBSTITUTED PYRIDOXINE-LACTAM CARBOXYLATE SALTS | PLPBP, PNPO, ADH5 | KDM4E 749/4885ALDH1A1 116/4885HPGD 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.