Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.53 |
| ▸ | THRA | P10827 | 11/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | PCNA | P12004 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124422 | 0.90 | PCNA (0.56) | THRBTHRACA2CA4PCNA | |
| SCHEMBL16124445 | 0.78 | PCNA (0.56) | THRBTHRAPCNAHPGDHSD17B10 | |
| SCHEMBL16124463 | 0.76 | PCNA (0.53) | THRBTHRAPCNAALDH1A1ERCC1 | |
| SCHEMBL16124418 | 0.76 | PCNA (0.63) | THRBTHRAPCNAHPGDHSD17B10 | |
| SCHEMBL16124501 | 0.76 | THRB (0.65) | THRBTHRAPCNAHPGDHSD17B10 | |
| SCHEMBL14553380 | 0.75 | THRB (0.52) | THRBTHRAPCNA | |
| SCHEMBL28413869 | 0.72 | THRA (0.61) | THRBTHRAKDM4EALDH1A1HPGD | |
| SCHEMBL2813680 | 0.70 | THRB (1.00) | THRBTHRA | |
| SCHEMBL23733121 | 0.69 | HDAC2 (0.59) | KDM4EALDH1A1HPGD | |
| SCHEMBL20439216 | 0.69 | HPGD (0.61) | THRBTHRACA2CA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006734-A1 | SUBSTITUTED 4-PHENOXYPHENOL ANALOGS AS MODULATORS OF PROLIFERATING CELL NUCLEAR ANTIGEN ACTIVITY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2013-01-10 | — | — | WO | disclosed |