Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553896 | 0.78 | HPGD (0.31) | HPGDSMN1; SMN2 | |
| SCHEMBL14554042 | 0.71 | PIM1 (0.30) | — | |
| SCHEMBL14554107 | 0.69 | — | — | |
| SCHEMBL14554041 | 0.69 | — | — | |
| SCHEMBL22743635 | 0.64 | ACHE (0.32) | ACHE | |
| SCHEMBL3021418 | 0.64 | HPGD (0.33) | HPGDSMN1; SMN2 | |
| SCHEMBL5571592 | 0.64 | L3MBTL1 (0.36) | SMN1; SMN2 | |
| SCHEMBL3291693 | 0.62 | ACHE (0.33) | ACHE | |
| SCHEMBL8553172 | 0.62 | PIK3CG (0.35) | SMN1; SMN2 | |
| SCHEMBL10916033 | 0.62 | SMPD3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013005041-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2013-01-10 | — | — | WO | disclosed |