SCHEMBL5571592

SCHEMBL5571592

O=C(O)c1cn2ccnc2c2c1CCCO2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
XDH P47989 1/20 0.34
SLC22A12 Q96S37 1/20 0.34
PDE10A Q9Y233 1/20 0.33
DHODH Q02127 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21819163 0.67 KDM4E (0.38) L3MBTL1SMN1; SMN2KDM4C
SCHEMBL31133522 0.67 KDM4E (0.38) L3MBTL1SMN1; SMN2KDM4C
SCHEMBL1816921 0.67 NUDT1 (0.35)
SCHEMBL23012585 0.65 L3MBTL1 (0.44) L3MBTL1XDHSLC22A12PDE10A
SCHEMBL12238197 0.65 L3MBTL1 (0.56) L3MBTL1XDHSLC22A12DHODHSMN1; SMN2
SCHEMBL6568411 0.64 SMN1; SMN2 (0.38) XDHSLC22A12SMN1; SMN2KDM4C
SCHEMBL21818593 0.64 ACHE (0.40) L3MBTL1SMN1; SMN2KDM4C
Hydrochloric Acid SCHEMBL15995962 0.64 L3MBTL1 (0.54) L3MBTL1XDHSLC22A12DHODHSMN1; SMN2
SCHEMBL14554102 0.64 HPGD (0.32) SMN1; SMN2
SCHEMBL15896720 0.62 XDH (0.42) L3MBTL1XDHSLC22A12DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070066674-A1 Tricyclic imidzopyridines for use as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2007-03-22 US disclosed
EP-1696921-A1 TRICYCLIC IMIDAZOPYRIDINES FOR USE AS GASTRIC SECRETION INHIBITORS Altana Pharma AG (DE) 2006-09-06 EP disclosed
WO-2005058325-A1 TRICYCLIC IMIDAZOPYRIDINES FOR USE AS GASTRIC SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2005-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066674-A1 Tricyclic imidzopyridines for use as gastric secretion inhibitors GIPR, SLC10A2, GRPR L3MBTL1 4766/4885XDH 2135/4885SLC22A12 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.