Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19392082 | 0.91 | CCR1 (0.49) | CCR1CCR5CCR8ALDH1A1L3MBTL1 | |
| SCHEMBL15906864 | 0.89 | CCR1 (0.39) | CCR1CCR5CCR8ALDH1A1L3MBTL1 | |
| SCHEMBL14554365 | 0.89 | HDAC1 (0.39) | CCR1CCR5CCR8ALDH1A1L3MBTL1 | |
| SCHEMBL17138168 | 0.78 | KCNA3 (0.46) | ALDH1A1L3MBTL1ALDH2MAOAMAOB | |
| SCHEMBL2533057 | 0.78 | CCR1 (0.50) | CCR1CCR5CCR8ALDH1A1MAOA | |
| SCHEMBL8553182 | 0.77 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1ALDH2MAOAMAOB | |
| SCHEMBL16581589 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1ALDH2MAOAMAOB | |
| SCHEMBL17138208 | 0.77 | PRSS1 (0.46) | ALDH1A1L3MBTL1ALDH2MAOAMAOB | |
| SCHEMBL16581610 | 0.75 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ALDH2MAOAMAOB | |
| SCHEMBL15365357 | 0.75 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1ALDH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9683004-B2 | Coated nanoparticles | THE UNIVERSITY OF BIRMINGHAM (GB) | 2017-06-20 | — | — | US | disclosed |
| US-9683004-B2 | Coated nanoparticles | THE UNIVERSITY OF BIRMINGHAM (GB) | 2017-06-20 | — | — | US | disclosed |
| US-9683004-B2 | Coated nanoparticles | THE UNIVERSITY OF BIRMINGHAM (GB) | 2017-06-20 | — | — | US | disclosed |
| US-20140212497-A1 | COATED NANOPARTICLES | THE UNIVERSITY OF BIRMINGHAM (GB) | 2014-07-31 | — | — | US | disclosed |
| US-20140212497-A1 | COATED NANOPARTICLES | THE UNIVERSITY OF BIRMINGHAM (GB) | 2014-07-31 | — | — | US | disclosed |
| US-20140212497-A1 | COATED NANOPARTICLES | THE UNIVERSITY OF BIRMINGHAM (GB) | 2014-07-31 | — | — | US | disclosed |
| WO-2013004989-A1 | COATED NANOPARTICLES | THE UNIVERSITY OF BIRMINGHAM (GB) | 2013-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212497-A1 | COATED NANOPARTICLES | CD63, PICALM, NCLN | CCR1 3339/4885CCR5 3314/4885CCR8 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.