Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 11/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636868 | 0.79 | CLTC (0.78) | CLTCNPSR1KDM4ECA12CA1 | |
| SCHEMBL9720994 | 0.78 | UBE2N (0.74) | CLTCNPSR1KDM4ECA12CA1 | |
| SCHEMBL8737445 | 0.75 | CASP3 (0.65) | NPSR1CA12CA1CA2CA9 | |
| SCHEMBL29820192 | 0.75 | CASP3 (0.65) | NPSR1CA12CA1CA2CA9 | |
| SCHEMBL13362952 | 0.74 | CASP3 (0.59) | NPSR1KDM4ECA12CA1CA2 | |
| SCHEMBL5594225 | 0.74 | NPSR1 (1.00) | CLTCNPSR1KDM4ECA12CA1 | |
| SCHEMBL12431376 | 0.73 | CA12 (0.60) | CLTCNPSR1KDM4ECA12CA1 | |
| SCHEMBL19529498 | 0.73 | MAPT (0.70) | NPSR1KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL28737144 | 0.73 | UBE2N (0.81) | CLTCNPSR1KDM4ECA12CA1 | |
| SCHEMBL28277900 | 0.73 | NPSR1 (0.73) | CLTCNPSR1KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030940-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-03-22 | — | — | WO | disclosed |