SCHEMBL145576

SCHEMBL145576

O=C(O)c1cccc(C(c2cccc(C(=O)O)c2C(=O)O)(C(F)(F)F)C(F)(F)F)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 2/20 0.42
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
FABP4 P15090 1/20 0.41
ALB P02768 1/20 0.40
LMNA P02545 2/20 0.40
AKR1C3 P42330 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.37
NR4A1 P22736 1/20 0.37
NR4A2 P43354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30269555 1.00 TAS2R14 (0.42) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL29404866 1.00 TAS2R14 (0.42) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL8713228 0.98 TAS2R14 (0.41) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL7095723 0.87 ALOX15 (0.43) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL4848176 0.87 HSD17B10 (0.40) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL9013418 0.85 ALDH1A1 (0.44) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL2964734 0.85 TAS2R14 (0.51) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL308976 0.85 HSD17B10 (0.41) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL7096331 0.84 TAS2R14 (0.39) TAS2R14ALDH1A1ALOX15MEN1KMT2A
SCHEMBL27075282 0.83 TAS2R14 (0.50) TAS2R14ALDH1A1ALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9791745-B2 Photoalignment polyimide copolymer and liquid crystal alignment layer LG CHEM, LTD. (KR) 2017-10-17 US claimed
US-20140072730-A1 Photoalignment Polyimide Copolymer and Liquid Crystal Alignment Layer LG CHEM, LTD. (KR) 2014-03-13 US claimed
EP-2209870-B1 PHOTOALIGNMENT AGENT OF LIQUID CRYSTAL, PHOTOALIGNMENT FILM OF LIQUID CRYSTAL INCLUDING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME CHEIL IND INC (KR) 2014-02-26 EP claimed
US-8425799-B2 Photoalignment agent of liquid crystal, photoalignment film of liquid crystal including the same, and liquid crystal display including the same CHEIL INDUSTRIES INC. (KR) 2013-04-23 US claimed
US-8057700-B2 Liquid crystal photo-alignment agent and liquid crystal photo-alignment film and liquid crystal display including the same CHEIL INDUSTRIES, INC. (KR) 2011-11-15 US claimed
JP-2011501208-A 2011-01-06 JP claimed
US-20100311900-A1 THERMALLY STABLE MATRIX MICROPARTICLES AND MICROCAPSULES FOR POLYMER ADDITIZATION AND PROCESS FOR THEIR PRODUCTION FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-12-09 US claimed
US-20100188628-A1 Photoalignment Agent of Liquid Crystal, Photoalignment Film of Liquid Crystal Including the Same, and Liquid Crystal Display Including the Same CHEIL INDUSTRIES INC. (KR) 2010-07-29 US claimed
EP-2209870-A1 PHOTOALIGNMENT AGENT OF LIQUID CRYSTAL, PHOTOALIGNMENT FILM OF LIQUID CRYSTAL INCLUDING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME Cheil Industries Inc. (KR) 2010-07-28 EP claimed
US-20100151155-A1 Liquid Crystal Alignment Agent and Liquid Crystal Alignment Film Manufactured Using the Same CHEIL INDUSTRIES INC. (KR) 2010-06-17 US claimed
US-20010023286-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thefeof SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-09-20 US claimed
EP-0957124-A1 Polyimides, process for producing the same and photosensitive composition containing the same Nippon Mektron, Limited (JP) 1999-11-17 EP claimed
EP-0957126-A1 Photosensitive composition Nippon Mektron, Limited (JP) 1999-11-17 EP claimed
EP-0624826-B1 Method of forming relief patterns by i-line light irradiation OCG MICROELECTRONIC MATERIALS (US) 1997-07-16 EP claimed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP claimed
EP-0699215-A1 CURABLE COMPOSITIONS ICI COMPOSITES INC. (US) 1996-03-06 EP claimed
EP-0368590-B1 Production process for polyimide fibers MITSUI TOATSU CHEMICALS (JP) 1995-01-25 EP claimed
WO-1994028051-A1 CURABLE COMPOSITIONS ICI COMPOSITES INC. (US) 1994-12-08 WO claimed
EP-0624826-A1 Method of forming relief patterns by i-line light irradiation OCG Microelectronic Materials Inc. (US) 1994-11-17 EP claimed
US-4927736-A Hydroxy polyimides and high temperature positive photoresists therefrom HOECHST CELANESE CORPORATION (US) 1990-05-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023286-A1 Optical polyimide precursor, optical polyimide compound and fabricating method thefeof POF1B, GTF2F1, MACF1 TAS2R14 671/4885ALDH1A1 4796/4885ALOX15 2490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.