Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.36 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.36 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.36 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.36 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611313 | 0.89 | CYP2D6 (0.44) | PPARDPPARAHPGDTBXAS1KDM4E | |
| SCHEMBL14558115 | 0.81 | FFAR1 (0.42) | ALDH1A1 | |
| SCHEMBL6003686 | 0.79 | TBXAS1 (0.44) | PPARDPPARATBXAS1PLA2G10PLA2G2A | |
| SCHEMBL6003677 | 0.79 | TBXAS1 (0.44) | PPARDPPARATBXAS1PLA2G10PLA2G2A | |
| SCHEMBL6005325 | 0.79 | TBXAS1 (0.44) | PPARDPPARATBXAS1PLA2G10PLA2G2A | |
| SCHEMBL31067929 | 0.79 | TBXAS1 (0.44) | PPARDPPARATBXAS1PLA2G10PLA2G2A | |
| SCHEMBL14558096 | 0.78 | HPGD (0.48) | PPARAHPGDTBXAS1PLA2G10PLA2G2A | |
| SCHEMBL28009302 | 0.75 | PLA2G10 (0.42) | PPARDPPARATBXAS1KDM4EPLA2G10 | |
| SCHEMBL15709740 | 0.75 | PLA2G10 (0.42) | PPARDPPARATBXAS1KDM4EPLA2G10 | |
| SCHEMBL15709334 | 0.75 | PLA2G10 (0.42) | PPARDPPARATBXAS1KDM4EPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-7179819-B2 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | PPARD 1974/4885PPARA 921/4885HPGD 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.