Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.43 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.43 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.43 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.43 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610928 | 0.88 | HPGD (0.50) | HPGDPLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL8257100 | 0.85 | TBXAS1 (0.53) | HPGDPLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL14558137 | 0.84 | CYP1A2 (0.47) | PLA2G10PLA2G2APPARA | |
| SCHEMBL14558136 | 0.82 | FOLH1 (0.45) | HTR2AADRA1ASLC6A3 | |
| SCHEMBL26732440 | 0.81 | AKR1B1 (0.46) | HPGDADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL1124990 | 0.81 | PLA2G10 (0.47) | HPGDPLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL14558135 | 0.81 | TBXAS1 (0.45) | HPGDTBXAS1ADRA2BADRA2CSLC6A2 | |
| SCHEMBL22388384 | 0.80 | ADRA2B (0.46) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL14558129 | 0.80 | CYP1A2 (0.40) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL1410876 | 0.79 | PLA2G10 (0.48) | HPGDPLA2G10PLA2G2APLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-7179819-B2 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | HPGD 4172/4885PLA2G10 1255/4885PLA2G2A 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.