Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13547377 | 0.89 | KDM4E (0.43) | KDM4EKAT2BMAPT | |
| SCHEMBL13547225 | 0.89 | KDM4E (0.46) | KDM4EMAPT | |
| SCHEMBL13547222 | 0.85 | KDM4E (0.45) | KDM4EMAPT | |
| SCHEMBL12811829 | 0.82 | EPHX1 (0.42) | KDM4EMAPT | |
| SCHEMBL13547213 | 0.81 | EPHX1 (0.49) | KDM4EMAPT | |
| SCHEMBL2676319 | 0.81 | EPHX1 (0.49) | KDM4EMAPT | |
| SCHEMBL13547356 | 0.79 | HTT (0.38) | KDM4ECA1CA2MAPT | |
| SCHEMBL25040953 | 0.79 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC4 | |
| SCHEMBL21464629 | 0.79 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC4 | |
| SCHEMBL14559362 | 0.78 | KMT2A (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186739-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |