Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30425794 | 0.85 | MAPT (0.39) | HDAC1HDAC2DRD2DRD3SSTR4 | |
| SCHEMBL9002622 | 0.83 | EPHX1 (0.45) | KMT2AHRH3 | |
| SCHEMBL14559369 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4DRD2DRD3 | |
| SCHEMBL21754480 | 0.80 | SMN1; SMN2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4SMN1; SMN2 | |
| SCHEMBL14559360 | 0.78 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21754477 | 0.77 | SMN1; SMN2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4SMN1; SMN2 | |
| SCHEMBL14559359 | 0.76 | MALT1 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL10212235 | 0.75 | DRD2 (0.46) | KMT2ASMN1; SMN2DRD2ALDH1A1MEN1 | |
| SCHEMBL16020326 | 0.75 | DRD2 (0.46) | KMT2ASMN1; SMN2DRD2ALDH1A1MEN1 | |
| SCHEMBL16020332 | 0.75 | DRD2 (0.46) | KMT2ASMN1; SMN2DRD2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186739-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |