Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | POLR1A | O95602 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14559359 | 0.96 | MALT1 (0.39) | CHRNB2CHRNA5CHRNA7CHRNA4CHRM3 | |
| SCHEMBL14559362 | 0.80 | KMT2A (0.37) | CHRNB2CHRNA4DRD2DRD3 | |
| SCHEMBL28645032 | 0.79 | DRD2 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4CHRM3 | |
| SCHEMBL30425794 | 0.78 | MAPT (0.39) | DRD2DRD3 | |
| SCHEMBL28649804 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4CHRM3 | |
| SCHEMBL9002622 | 0.76 | EPHX1 (0.45) | — | |
| SCHEMBL8055435 | 0.74 | EPHX1 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4CHRM3 | |
| SCHEMBL8038051 | 0.74 | EPHX1 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4CHRM3 | |
| SCHEMBL11240147 | 0.74 | OPRM1 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B | |
| SCHEMBL12506716 | 0.73 | FAP (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186739-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |