Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647161 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1BLMNATACR1CASR | |
| SCHEMBL2091812 | 0.79 | MTNR1A (0.67) | MTNR1AMTNR1BLMNATACR1BCAT2 | |
| SCHEMBL2726717 | 0.78 | LMNA (0.53) | MTNR1AMTNR1BLMNATACR1BCAT2 | |
| SCHEMBL13480537 | 0.78 | NPSR1 (0.58) | PKMMEN1KMT2ALMNACASR | |
| SCHEMBL8005868 | 0.77 | POLB (0.60) | PKMMEN1KMT2ALMNACASR | |
| SCHEMBL9504011 | 0.77 | HTT (0.52) | — | |
| SCHEMBL10154589 | 0.76 | CASR (0.69) | MEN1KMT2ALMNACASRPOLB | |
| SCHEMBL12000489 | 0.76 | KMT2A (0.53) | MEN1KMT2AMTNR1AMTNR1BLMNA | |
| SCHEMBL8923076 | 0.75 | EPHX2 (0.67) | LMNAEPHX2 | |
| SCHEMBL753128 | 0.75 | NAALAD2 (0.59) | PKMMEN1KMT2ACASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186725-B2 | Anti-inflammatory compositions and methods | GENZYME CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186725-B2 | Anti-inflammatory compositions and methods | GENZYME CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |