Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562118 | 0.82 | KDM4E (0.48) | GAAKDM4EHTTMEN1KMT2A | |
| SCHEMBL5423393 | 0.82 | GABRA5 (0.50) | KDM4EHTTMEN1KMT2AMAPT | |
| SCHEMBL14562117 | 0.79 | ALDH1A1 (0.62) | HTTKMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5424070 | 0.78 | PTGS2 (0.57) | GAAKDM4EHTTMEN1KMT2A | |
| SCHEMBL14562155 | 0.71 | PTGS2 (0.48) | GAAHTTMEN1KMT2AMAPT | |
| SCHEMBL5655209 | 0.71 | NPC1 (0.65) | SMN1; SMN2HPGD | |
| SCHEMBL14562122 | 0.70 | GABRA5 (0.51) | PTGS2MT-CO2NR4A2GABRA5PTGS1 | |
| SCHEMBL14562134 | 0.70 | GABRA5 (0.63) | GAAPTGS2MT-CO2NR4A2GABRA5 | |
| SCHEMBL14562102 | 0.69 | PTGS2 (0.60) | GAAHTTMEN1KMT2AMAPT | |
| SCHEMBL5429944 | 0.69 | PTGS2 (0.65) | MAPTPTGS2MT-CO2NR4A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060629-A1 | Large conductance calcium-activated k channel opener | TANABE SEIYAKU CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| US-20070060629-A1 | Large conductance calcium-activated k channel opener | TANABE SEIYAKU CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060629-A1 | Large conductance calcium-activated k channel opener | KCNN3, KCNN1, KCNN2 | GAA 4384/4885KDM4E 722/4885HTT 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.