Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64502 | 0.91 | ALDH1A1 (0.72) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1505883 | 0.87 | MEN1 (0.64) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL21026201 | 0.85 | ALDH1A1 (0.66) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL5457556 | 0.81 | NPC1 (0.62) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL29244993 | 0.81 | ALDH1A1 (0.78) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL12472851 | 0.81 | ALDH1A1 (0.74) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL10216153 | 0.81 | NPC1 (0.67) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL18821732 | 0.81 | NPC1 (0.67) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL13264716 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL71303 | 0.79 | TSHR (0.69) | ALDH1A1HPGDNPC1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072915-A1 | Novel phenoxyacetamide derivative and use thereof for preparation of diphenylamines | MERCK PATENT GMBH (DE) | 2007-03-29 | — | — | US | disclosed |
| US-20070072915-A1 | Novel phenoxyacetamide derivative and use thereof for preparation of diphenylamines | MERCK PATENT GMBH (DE) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072915-A1 | Novel phenoxyacetamide derivative and use thereof for preparation of diphenylamines | PNMT, AADAC, INMT | ALDH1A1 861/4885HPGD 604/4885NPC1 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.