SCHEMBL1456409

SCHEMBL1456409

CCO[SiH](OCC)C(C)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.33
CACNA2D1 P54289 2/20 0.32
CACNB3 P54284 1/20 0.32
CACNA1C Q13936 1/20 0.32
PGR P06401 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
CACNA2D2 Q9NY47 1/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32
GABRA4 P48169 2/20 0.32
GABRE P78334 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11905927 0.75 GNPAT (0.33)
SCHEMBL30880227 0.73 TP53 (0.33) ADRA1AGABRPGABRDGABRA1GABRB1
SCHEMBL125174 0.71 LMNA (0.32)
Ethane SCHEMBL5834544 0.69 LMNA (0.30)
SCHEMBL7094369 0.68 ALDH1A1 (0.44) PGRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL4077417 0.67
SCHEMBL3103583 0.67
SCHEMBL10697771 0.67 ALDH1A1 (0.32) ALDH1A1
SCHEMBL1608027 0.67 TSHR (0.31)
SCHEMBL8852110 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017093759-A1 FUNCTIONALISATION METHOD FOR METAL OXIDE PARTICLES THE WELDING INSTITUTE (GB) 2017-06-08 WO disclosed
US-7910216-B2 Process for the production of organosilsesquioxanes THE WELDING INSTITUTE (GB) 2011-03-22 US disclosed
EP-1957563-B1 PROCESS FOR THE PRODUCTION OF ORGANOSILSESQUIOXANES WELDING INST (GB) 2010-04-28 EP disclosed
US-20090108488-A1 Process for Production of Hybrid Polymeric Material KANEKA CORPORATION (JP) 2009-04-30 US disclosed
EP-1957563-A1 PROCESS FOR THE PRODUCTION OF ORGANOSILSESQUIOXANES THE WELDING INSTITUTE (GB) 2008-08-20 EP disclosed
US-7326762-B2 Copolymer having reactive silicon-containing group and organic-inorganic hybrid polymeric material ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2008-02-05 US disclosed
EP-1295903-B1 Polymeric material, molded product and methods for their production ORIENT CHEMICAL IND (JP) 2007-11-07 EP disclosed
EP-0918061-B1 Organic-inorganic hybrid polymer material and process for preparing the same ORIENT CHEMICAL IND (JP) 2007-10-31 EP disclosed
WO-2007060387-A1 PROCESS FOR THE PRODUCTION OF ORGANOSILSESQUIOXANES THE WELDING INSTITUTE (GB) 2007-05-31 WO disclosed
US-20070122636-A1 PROCESS FOR THE PRODUCTION OF ORGANOSILSESQUIOXANES THE WELDING INSTITUTE (GB) 2007-05-31 US disclosed
US-6476098-B1 Organic-inorganic composite material and process for preparing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-05 US disclosed
US-20020122891-A1 Organic-inorganic hybrid polymer materials with compositional gradient, and processes for preparing the same ARAKAWA MOTOOMI (JP) 2002-09-05 US disclosed
US-6395341-B1 ORGANIC POLYMER AND METAL ALKOXIDE ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-28 US disclosed
WO-2002024824-A1 COATING COMPOSITIONS THE WELDING INSTITUTE (GB) 2002-03-28 WO disclosed
US-6228796-B1 ORGANIC-INORGANIC HYBRID MATERIAL, SURFACE OF WHICH IS SUPPLIED WITH LAYER HAVING PHOTO-CATALYSIS, WITHOUT PHOTO-DEGRADATION OF SUBSTRATE ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-08 US disclosed
EP-1054035-A2 Organic-inorganic composite material and process for preparing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2000-11-22 EP disclosed
US-6103854-A POLYMER HAVING A POLYCARBONATE AND/OR A POLYARYLATE MOIETY AS A MAIN FRAME AND HAVING A METAL ALKOXIDE GROUP AS A FUNCTIONAL GROUP, IS HYDROLYZED AND POLYCONDENSED TO FORM CROSSLINKAGES; HEAT RESISTANCE, HARDNESS, STRENGTH ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2000-08-15 US disclosed
EP-1016458-A2 Photocatalyst comprising organic-inorganic hybrid materials, and processes for preparing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2000-07-05 EP disclosed
EP-0972809-A2 Organic-inorganic hybrid polymer materials with compositional gradient, and processes for preparing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2000-01-19 EP disclosed
EP-0918061-A2 Organic-inorganic hybrid polymer material and process for preparing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1999-05-26 EP disclosed