Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26828140 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTTP53RAB9AKDM4E | |
| SCHEMBL8496933 | 0.82 | TDP1 (0.50) | ALDH1A1MAPTTP53RAB9AKDM4E | |
| SCHEMBL18780592 | 0.82 | RAB9A (0.53) | ALDH1A1MAPTTP53RAB9ASMN1; SMN2 | |
| SCHEMBL2025855 | 0.82 | RAB9A (0.49) | ALDH1A1MAPTTP53RAB9ASMN1; SMN2 | |
| SCHEMBL13996243 | 0.80 | RAB9A (0.51) | ALDH1A1MAPTTP53RAB9ASMN1; SMN2 | |
| SCHEMBL29190317 | 0.79 | TPSAB1 (0.51) | ALDH1A1MAPTTP53RAB9AKDM4E | |
| SCHEMBL14871086 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTTP53RAB9AKDM4E | |
| SCHEMBL14012787 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTTP53RAB9AKDM4E | |
| SCHEMBL26815332 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTTP53RAB9AKDM4E | |
| SCHEMBL14446152 | 0.77 | L3MBTL1 (0.66) | ALDH1A1RAB9AKDM4EGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033175-A1 | INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |