Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.80 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12338860 | 0.93 | GFER (0.86) | GFERCA12CA9MAPTALDH1A1 | |
| SCHEMBL15702654 | 0.89 | MAPT (0.83) | GFERCA12CA9MAPTHPGD | |
| SCHEMBL15705237 | 0.88 | FFAR1 (0.68) | GFERCA12CA9MAPTHPGD | |
| SCHEMBL4090549 | 0.84 | MAPT (0.70) | CA12CA9MAPTHPGDALDH1A1 | |
| SCHEMBL8227909 | 0.84 | GFER (0.72) | GFERCA12CA9ALDH1A1CA1 | |
| SCHEMBL665556 | 0.84 | GFER (0.72) | GFERCA12CA9ALDH1A1CA1 | |
| SCHEMBL3554284 | 0.83 | ALDH1A1 (0.67) | GFERCA12CA9MAPTHPGD | |
| SCHEMBL5316220 | 0.83 | MAPT (0.68) | GFERCA12CA9MAPTHPGD | |
| SCHEMBL5317270 | 0.81 | CA12 (0.63) | GFERCA12CA9MAPTHPGD | |
| SCHEMBL13028454 | 0.81 | GFER (0.67) | GFERCA12CA9ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066623-A1 | Entry inhibitors of the hiv virus | JANSSEN R&D IRELAND (IE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066623-A1 | Entry inhibitors of the hiv virus | HAVCR2, CCR5, SAMHD1 | GFER 4242/4885CA12 3621/4885CA9 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.