SCHEMBL14569487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14610823	0.89	EPHX2 (0.43)	EPHX2RIPK1HDAC1HDAC6HDAC2
	SCHEMBL14569489	0.87	EPHX2 (0.47)	EPHX2RIPK1ADAM17
	SCHEMBL14557708	0.86	EPHX2 (0.41)	EPHX2RIPK1HDAC1HDAC6HDAC2
	SCHEMBL14569804	0.81	EPHX2 (0.38)	EPHX2RIPK1ADAM17
	SCHEMBL14569488	0.81	EPHX2 (0.40)	EPHX2RIPK1ADAM17
	SCHEMBL14610825	0.76	EPHX2 (0.46)	EPHX2RIPK1ADAM17
	SCHEMBL14557696	0.73	EPHX2 (0.43)	EPHX2RIPK1ADAM17
	SCHEMBL17454944	0.73	RIPK1 (0.69)	EPHX2RIPK1
	SCHEMBL8275419	0.73	RIPK1 (0.69)	EPHX2RIPK1
	SCHEMBL14611020	0.72	EPHX2 (0.39)	EPHX2RIPK1ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.