Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PTEN | P60484 | 1/20 | 0.40 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610825 | 0.88 | EPHX2 (0.46) | EPHX2RIPK1ADAM17TMEM97SIGMAR1 | |
| SCHEMBL14569487 | 0.87 | EPHX2 (0.45) | EPHX2RIPK1ADAM17 | |
| SCHEMBL14557696 | 0.85 | EPHX2 (0.43) | EPHX2RIPK1ADAM17TMEM97SIGMAR1 | |
| SCHEMBL14569486 | 0.85 | HRH3 (0.50) | EPHX2RIPK1HRH3HPGDSMN1; SMN2 | |
| SCHEMBL14569571 | 0.80 | KDM4E (0.44) | RIPK1ADAM17HRH3HPGD | |
| SCHEMBL17454944 | 0.78 | RIPK1 (0.69) | EPHX2RIPK1HSP90AA1HSP90AB1POLB | |
| SCHEMBL8275419 | 0.78 | RIPK1 (0.69) | EPHX2RIPK1HSP90AA1HSP90AB1POLB | |
| SCHEMBL14558757 | 0.78 | TMEM97 (0.47) | EPHX2RIPK1ADAM17TMEM97SIGMAR1 | |
| SCHEMBL14569804 | 0.78 | EPHX2 (0.38) | EPHX2RIPK1ADAM17 | |
| SCHEMBL14569488 | 0.78 | EPHX2 (0.40) | EPHX2RIPK1ADAM17TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | EPHX2 3415/4885RIPK1 4081/4885ADAM17 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.