Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573192 | 0.87 | KDM4E (0.47) | KCNH2HRH1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL14113589 | 0.83 | OPRD1 (0.68) | CYP3A4CYP2C9CYP2B6CYP2J2 | |
| SCHEMBL14020878 | 0.80 | HRH1 (0.65) | KCNH2HRH1HTTRECQLNPSR1 | |
| SCHEMBL6362147 | 0.78 | KCNH2 (0.83) | KCNH2HRH1HTTRECQLNPSR1 | |
| SCHEMBL10479209 | 0.77 | HRH1 (0.63) | KCNH2HRH1 | |
| SCHEMBL55533 | 0.77 | HRH1 (0.67) | KCNH2HRH1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL28021507 | 0.77 | HTT (0.63) | KCNH2HRH1CYP2C9HTTRECQL | |
| SCHEMBL10568072 | 0.77 | HRH1 (0.62) | KCNH2HRH1 | |
| SCHEMBL9786914 | 0.76 | HRH1 (0.66) | KCNH2HRH1CYP2J2 | |
| SCHEMBL3240024 | 0.75 | KCNH2 (0.78) | KCNH2HRH1CYP3A4CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |