Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684013 | 0.81 | NFE2L2 (0.56) | TP53SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL3492741 | 0.81 | KAT6A (0.51) | TP53CYP3A4KAT6ACHRM2CHRM1 | |
| SCHEMBL9058916 | 0.81 | TP53 (0.53) | TP53CYP3A4KAT6ACHRM2CHRM1 | |
| SCHEMBL11340502 | 0.80 | LMNA (0.63) | TP53SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL14773591 | 0.80 | TP53 (0.52) | TP53CYP3A4KAT6ACHRM2CHRM1 | |
| SCHEMBL13592998 | 0.80 | TP53 (0.52) | TP53CYP3A4KAT6ACHRM2CHRM1 | |
| SCHEMBL29469874 | 0.78 | CA1 (0.62) | TP53CYP3A4KAT6ALMNAKDM4E | |
| SCHEMBL5610159 | 0.78 | CA1 (0.62) | TP53CYP3A4KAT6ALMNAKDM4E | |
| SCHEMBL3283827 | 0.78 | TP53 (0.50) | TP53CYP3A4KAT6ACHRM2CHRM1 | |
| SCHEMBL5610156 | 0.78 | KAT6A (0.51) | TP53CYP3A4KAT6ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |