Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817806 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL6688903 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL74521 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDKMT2AMEN1POLB | |
| SCHEMBL21311562 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL28195774 | 0.80 | POLB (0.64) | HPGDKMT2AMEN1MAPTPOLB | |
| SCHEMBL30702637 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL2307143 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL15761128 | 0.79 | MAPT (0.41) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL5725423 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL14575994 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10220100-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM KEITH R (US) | 2019-03-05 | — | — | US | disclosed |
| US-20180369395-A9 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | LATHAM KEITH R (US) | 2018-12-27 | — | — | US | disclosed |
| US-20180117164-A1 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | LATHAM KEITH R (US) | 2018-05-03 | — | — | US | disclosed |
| US-9144613-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM KEITH R (US) | 2015-09-29 | — | — | US | disclosed |
| US-9125946-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM KEITH R (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140134105-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | LATHAM KEITH R (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140135397-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | LATHAM KEITH R (US) | 2014-05-15 | — | — | US | disclosed |
| US-8673269-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM, KEITH | 2014-03-18 | — | — | US | disclosed |
| US-20130022549-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | LATHAM, KEITH | 2013-01-24 | — | — | US | disclosed |
| US-20130018026-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | IPE, INC. | 2013-01-17 | — | — | US | disclosed |
| US-20130017163-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | IPE, INC. | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018026-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | COMT, GPX4, GPX1 | ALDH1A1 614/4885HPGD 606/4885KMT2A 3407/4885 |
| US-20140134105-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | LPO, AHR, TDO2 | ALDH1A1 343/4885HPGD 273/4885KMT2A 3314/4885 |
| US-20180369395-A9 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | COMT, GPX4, GPX1 | ALDH1A1 614/4885HPGD 606/4885KMT2A 3407/4885 |
| US-10220100-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | COMT, GPX4, GPX1 | ALDH1A1 614/4885HPGD 606/4885KMT2A 3407/4885 |
| US-20180117164-A1 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | COMT, GPX4, GPX1 | ALDH1A1 614/4885HPGD 606/4885KMT2A 3407/4885 |
| US-20140135397-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | COMT, GPX4, GPX1 | ALDH1A1 614/4885HPGD 606/4885KMT2A 3407/4885 |
| US-20130022549-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | LPO, AHR, TDO2 | ALDH1A1 343/4885HPGD 273/4885KMT2A 3314/4885 |
| US-20130017163-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | TYR, PRDX5, PPARG | ALDH1A1 865/4885HPGD 756/4885KMT2A 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.