Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940602 | 1.00 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL222435 | 0.85 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29825539 | 0.85 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17823303 | 0.83 | MEN1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29538723 | 0.83 | ALDH1A1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1020510 | 0.83 | ACHE (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11415006 | 0.83 | APLNR (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL374346 | 0.83 | ALDH1A1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6117909 | 0.81 | APLNR (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6113969 | 0.81 | APLNR (0.40) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265382-A | A kind of fluorine-containing thiocarbamates compound and its synthetic method | 湖北科技学院 | 2019-01-25 | — | — | CN | claimed |
| CN-106966990-A | A kind of synthetic method of the polysubstituted ketone compounds of 2 thiocarbamoyl imidazole quinoline 4 | 湖北科技学院 | 2017-07-21 | — | — | CN | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-105267967-A | Combined application of isothiocyanate-type compound and anti-cancer drug acting or affecting DNA | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2016-01-27 | — | — | CN | claimed |
| CN-104415332-A | Combined application between isothiocyanate-type compound and kinase inhibitor medicine in treatment of cancer | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2015-03-18 | — | — | CN | claimed |
| CN-104117064-A | Combined application of isothiocyanate compound and hormone medicine | WUXI JC PHARMACAUTICAL TECHNOLOGY INC | 2014-10-29 | — | — | CN | claimed |
| WO-2025106383-A1 | PYRROLIDINYL DERIVATIVES USEFUL AS HCN1/HCN 2 MODULATORS | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-3446689-B1 | ISOTHIOCYANATE COMPOUND FOR USE IN THE TREATMENT OF HYPERBILIRUBINEMIA | JC WUXI COMPANY INC (CN) | 2025-01-08 | — | — | EP | disclosed |
| CN-113262218-B | Use of isothiocyanate compounds | 无锡杰西医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| EP-3383378-B1 | METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA) | PROCTER & GAMBLE (US) | 2024-04-17 | — | — | EP | disclosed |
| US-11298334-B2 | Use of isothiocyanate compounds | JC (WUXI) COMPANY, INC. (CN) | 2022-04-12 | — | — | US | disclosed |
| CN-113262218-A | Application of isothiocyanate compounds | 无锡杰西医药股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-1391446-A | Products comprising isothiocyanate preservative system and methods of their use | PROCTER & GAMBLE (US) | 2003-01-15 | — | — | CN | disclosed |
| EP-1229805-A1 | Beverage products comprising a preservative system consisting of an isothiocyanate in combination with a sorbate and/or a benzoate | THE PROCTER & GAMBLE COMPANY (US) | 2002-08-14 | — | — | EP | disclosed |
| US-20020061352-A1 | Products comprising an isothiocyanate preservative system and methods of their use | ALBION LABORATORIES, INC. (FORMERLY ALBION INTERNATIONAL, INC.) | 2002-05-23 | — | — | US | disclosed |
| US-6361812-B1 | WITH PRESERVATIVES SELECTED FROM SORBATE AND BENZOATE PRESERVATIVES; FOR FOOD OR BEVERAGE PRODUCTS | THE PROCTER & GAMBLE CO. | 2002-03-26 | — | — | US | disclosed |
| WO-2001035769-A1 | PRODUCTS COMPRISING AN ISOTHIOCYANATE PRESERVATIVE SYSTEM AND METHODS OF THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
| US-4845020-A | ANTIFOGGANT, SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4634660-A | ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1987-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | CA12 1582/4885CA1 1745/4885CA2 924/4885 |
| US-11298334-B2 | Use of isothiocyanate compounds | LIPC, CETP, LCAT | CA12 3660/4885CA1 4418/4885CA2 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.