Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578330 | 0.79 | CTSS (0.39) | MAPK1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14578020 | 0.77 | LMNA (0.47) | ALOX15LMNAMAPK1ALDH1A1SLC6A2 | |
| SCHEMBL14578026 | 0.77 | LMNA (0.47) | ALOX15LMNAMAPK1ALDH1A1SLC6A2 | |
| SCHEMBL167430 | 0.76 | ALOX15 (0.48) | ALOX15LMNAMAPK1SLC6A2SLC6A4 | |
| SCHEMBL11142447 | 0.76 | CYP2D6 (0.47) | ALOX15LMNAALDH1A1SLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL9292400 | 0.75 | ALOX15 (0.47) | ALOX15LMNAMAPK1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8044031 | 0.75 | LMNA (0.47) | ALOX15LMNAMAPK1SLC6A2SLC6A4 | |
| SCHEMBL9842268 | 0.73 | LMNA (0.48) | ALOX15LMNAMAPK1ALDH1A1SLC6A2 | |
| SCHEMBL16672851 | 0.73 | FFAR1 (0.49) | ALOX15ALDH1A1GABBR2GABBR1 | |
| SCHEMBL28444913 | 0.73 | ALOX15 (0.45) | ALOX15LMNAMAPK1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |