Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292110 | 0.81 | CTSS (0.42) | CTSSCTSKRIPK1SLC6A4CYP2D6 | |
| SCHEMBL5407416 | 0.81 | CYP1A1 (0.42) | SLC6A4CYP2D6SLC6A2SLC6A3KCNH2 | |
| SCHEMBL5407413 | 0.81 | CYP1A1 (0.42) | SLC6A4CYP2D6SLC6A2SLC6A3KCNH2 | |
| SCHEMBL14578329 | 0.81 | CYP1A1 (0.42) | SLC6A4CYP2D6SLC6A2SLC6A3KCNH2 | |
| SCHEMBL16672751 | 0.80 | L3MBTL1 (0.41) | CTSSCTSKRIPK1PTPN1L3MBTL1 | |
| SCHEMBL14578027 | 0.79 | ALOX15 (0.42) | GAASLC6A4SLC6A2SLC6A3KDM4E | |
| SCHEMBL16713307 | 0.78 | ALDH1A1 (0.39) | CTSSCTSKPTPN1L3MBTL1ALDH1A1 | |
| SCHEMBL5410221 | 0.73 | SLC6A3 (0.41) | GAASLC6A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL14578291 | 0.73 | SLC6A3 (0.41) | GAASLC6A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL28857505 | 0.73 | RIPK1 (0.51) | CTSSCTSKRIPK1CYP2D6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |