Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 11/20 | 0.63 |
| ▸ | NPC1 | O15118 | 10/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978809 | 0.83 | RAB9A (0.73) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL8784838 | 0.83 | RAB9A (0.69) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL978808 | 0.83 | RAB9A (0.73) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL11975139 | 0.83 | KMT2A (0.55) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL5524662 | 0.82 | RAB9A (0.71) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL2884065 | 0.82 | ALDH1A1 (0.59) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9613720 | 0.81 | RAB9A (0.70) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9613726 | 0.81 | RAB9A (0.70) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL14376787 | 0.80 | KCNMA1 (0.58) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL27677695 | 0.80 | KCNMA1 (0.53) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176320-B2 | Benzimidazole derivative | TEIJIN LIMITED (JP) | 2007-02-13 | — | — | US | disclosed |
| US-7176320-B2 | Benzimidazole derivative | TEIJIN LIMITED (JP) | 2007-02-13 | — | — | US | disclosed |