Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618053 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL10014116 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL14565715 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL1618051 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL6421580 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL1617431 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL15144383 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL110177 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL4749641 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA | |
| SCHEMBL19809887 | 1.00 | LMNA (0.65) | LMNAKDM4EAPOBEC3AAPOBEC3GGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | disclosed |
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-02-01 | — | — | US | disclosed |
| WO-2018131575-A1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | 高砂香料工業株式会社 | 2018-07-19 | — | — | WO | disclosed |
| US-7189760-B2 | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine | MILLENNIUM SPECIALTY CHEMICALS (US) | 2007-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TRPM8, TRPM4, TRPM2 | LMNA 2092/4885KDM4E 2712/4885APOBEC3A 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.