SCHEMBL1617431

SCHEMBL1617431

CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OCC(O)CO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.65
KDM4E B2RXH2 1/20 0.62
APOBEC3A P31941 1/20 0.62
APOBEC3G Q9HC16 1/20 0.62
GAA P10253 1/20 0.61
ALDH1A1 P00352 4/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
NTSR1 P30989 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MAPT P10636 1/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
XBP1 P17861 1/20 0.53
CYP2C19 P33261 1/20 0.53
TRPA1 O75762 2/20 0.43
TRPM8 Q7Z2W7 2/20 0.43
P2RX4 Q99571 1/20 0.43
EPHX1 P07099 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618053 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL14580754 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL10014116 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL14565715 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL1618051 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL6421580 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL15144383 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL110177 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL4749641 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL19809887 1.00 LMNA (0.65) LMNAKDM4EAPOBEC3AAPOBEC3GGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924642-A High-tear-resistance heat-resistant poly (siloxane-urethane) material and preparation method thereof 常州大学 2024-04-26 CN claimed
CN-117813077-A Composition and method for producing the same 西姆莱斯股份公司 2024-04-02 CN claimed
CN-117615798-A Composition for combating malodour 西姆莱斯股份公司 2024-02-27 CN claimed
CN-113952388-A Traditional Chinese medicine composition for oral bacteriostasis and preparation method thereof 贵州医之星药业有限公司 2022-01-21 CN claimed
WO-2018116202-A1 STABILIZED MOUTH FRESHENER STRIPS AZISTA INDUSTRIES PVT LTD (IN) 2018-06-28 WO claimed
CN-104188942-A Transdermal absorption promoter, and external skin formulation thereof TAKASAGO PERFUMERY CO LTD 2014-12-10 CN claimed
US-20140219931-A1 P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COOLING SENSATION COMPOSITION COMPRISING THE SAME, AND PRODUCT COMPRISING THE COOLING SENSATION COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-08-07 US claimed
EP-2725900-A1 ANTIMICROBIAL COMPOSITION Takasago International Corporation (JP) 2014-05-07 EP claimed
US-20130136704-A1 P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COMPOSITION COMPRISING THE SAME, AND PRODUCTS COMPRISING THE MIXTURE OR COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-30 US claimed
EP-2582357-A1 TRANSDERMAL ABSORPTION PROMOTER, AND EXTERNAL SKIN FORMULATION THEREOF Takasago International Corporation (JP) 2013-04-24 EP claimed
CN-102939075-A Percutaneous absorption promoter and external skin preparation thereof TAKASAGO PERFUMERY CO LTD 2013-02-20 CN claimed
WO-2013002421-A1 ANTIMICROBIAL COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-01-03 WO claimed
US-20130005807-A1 ANTIMICROBIAL COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-01-03 US claimed
EP-1761238-B1 MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME TAKASAGO PERFUMERY CO LTD (JP) 2012-09-05 EP claimed
WO-2011158964-A1 TRANSDERMAL ABSORPTION PROMOTER, AND EXTERNAL SKIN FORMULATION THEREOF TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-12-22 WO claimed
US-7923585-B2 Menthol derivative and cooling agent composition comprising the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-04-12 US claimed
US-20070225378-A1 Menthol Dearivative and Cooling Agent Composition Comprising the Same TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-09-27 US claimed
EP-1615974-B1 NON-TOXIC COATING COMPOSITION, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS SYMRISE GMBH & CO KG (DE) 2007-04-04 EP claimed
EP-1761238-A1 MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME Takasago International Corporation (JP) 2007-03-14 EP claimed
WO-2005115325-A1 MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-12-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140219931-A1 P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COOLING SENSATION COMPOSITION COMPRISING THE SAME, AND PRODUCT COMPRISING THE COOLING SENSATION COMPOSITION TRPM8, TAS2R8, TRPM7 LMNA 2223/4885KDM4E 1928/4885APOBEC3A 3860/4885
US-20070225378-A1 Menthol Dearivative and Cooling Agent Composition Comprising the Same TRPM7, TRPA1, TRPM2 LMNA 2154/4885KDM4E 614/4885APOBEC3A 2485/4885
US-20130136704-A1 P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COMPOSITION COMPRISING THE SAME, AND PRODUCTS COMPRISING THE MIXTURE OR COMPOSITION TRPM8, NAPEPLD, TRPM4 LMNA 1199/4885KDM4E 1751/4885APOBEC3A 3610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.