Sugi Predict

Sugi Predict / Compounds / Biphenyl

Biphenyl

Biphenyl

SCHEMBL1458263

O=c1cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.69
▸ LMNA P02545 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ ATM Q13315 1/20 0.50
▸ CTRC Q99895 1/20 0.48
▸ HSD17B10 Q99714 2/20 0.48
▸ CFTR P13569 1/20 0.48
▸ GOPC Q9HD26 1/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ NFKB1 P19838 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ NFKB2 Q00653 1/20 0.48
▸ RELA Q04206 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ PLA2G10 O15496 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ NOTUM Q6P988 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31274575 0.85 NOTUM (0.54) ALDH1A1LMNAMAPTHTTATM
SCHEMBL30629023 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
Biphenyl SCHEMBL29008551 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
SCHEMBL30108088 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
Biphenyl SCHEMBL4002609 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
Biphenyl SCHEMBL28890607 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
Biphenyl SCHEMBL2548048 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
Biphenyl SCHEMBL164 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
Biphenyl SCHEMBL1358618 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM
SCHEMBL29560186 0.83 ALDH1A1 (1.00) ALDH1A1LMNAMAPTHTTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118317951-A Phthalazine derivatives as pyruvate kinase modulators 西特瑞治疗有限公司 2024-07-09 — — CN claimed
CN-115844809-A Micro-needle for treating alopecia and preparation method thereof 媄典(北京)医疗器械有限公司 2023-03-28 — — CN claimed
CN-112898256-B Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound 遵义医科大学 2023-01-31 — — CN claimed
CN-112174880-B Preparation method of 1,3,4, 6-tetra-substituted pyridone derivative 华侨大学 2022-07-29 — — CN claimed
CN-111087401-B Novel method for establishing spiro ring on 2-aryl quinazoline-4 (3H) -ketone compound 四川大学 2022-05-17 — — CN claimed
CN-114099936-A Long-acting soluble microneedle for cosmetic filling and sustained-release administration and preparation method thereof 江苏熙美生物科技有限公司 2022-03-01 — — CN claimed
US-11207511-B2 Methods for treating baldness and promoting hair growth FOLLICA, INC. (US) 2021-12-28 — — US claimed
US-20210299036-A1 CONDITIONED MEDIUM AND EXTRACELLULAR MATRIX COMPOSITIONS AND USES THEREOF ALLERGAN SALES, LLC 2021-09-30 — — US claimed
EP-3829607-A1 CONDITIONED MEDIUM AND EXTRACELLULAR MATRIX COMPOSITIONS AND USES THEREOF Histogen, Inc. (US) 2021-06-09 — — EP claimed
CN-112898256-A Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound 遵义医科大学 2021-06-04 — — CN claimed
CN-107119297-A A kind of oil field tube and its electro-plating method and plating materials 胜利油田胜鑫防腐有限责任公司 2017-09-01 — — CN claimed
CN-106905205-A An a kind of step constructs C O and C Bifunctionalized products of S keys and preparation method thereof 安徽师范大学 2017-06-30 — — CN claimed
CN-103965165-B A kind of isoquinoline compound suppressing IAP and preparation method and application 复旦大学 2017-01-04 — — CN claimed
CN-105949152-A Benzofuran derivative and preparation method thereof 安徽师范大学 2016-09-21 — — CN claimed
CN-103965165-A Isoquinoline compounds capable of inhibiting inhibitor-of-apoptosis proteins and preparation method and application of isoquinoline compounds UNIV FUDAN 2014-08-06 — — CN claimed
US-20140079686-A1 Methods For Treating Baldness And Promoting Hair Growth FOLLICA, INC. 2014-03-20 — — US claimed
EP-2648676-A1 METHODS FOR TREATING BALDNESS AND PROMOTING HAIR GROWTH Follica, Inc. (US) 2013-10-16 — — EP claimed
WO-2012078649-A1 METHODS FOR TREATING BALDNESS AND PROMOTING HAIR GROWTH FOLLICA, INC. (US) 2012-06-14 — — WO claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 — — US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140079686-A1 Methods For Treating Baldness And Promoting Hair Growth AREG, FGF1, NGF ALDH1A1 1325/4885LMNA 2717/4885MAPT 3164/4885
US-11207511-B2 Methods for treating baldness and promoting hair growth AREG, FGF1, NGF ALDH1A1 1325/4885LMNA 2717/4885MAPT 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.