SCHEMBL1458348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1457783	0.86	CA12 (0.55)	CA12CA1CA2CA7CA9
	SCHEMBL9944152	0.85	RORC (0.43)	CA12CA1CA2CA7CA9
	SCHEMBL1458345	0.84	ALDH1A1 (0.58)	LMNAALDH1A1MAPTMEN1KMT2A
	SCHEMBL1457790	0.83	GAA (0.47)	CA12CA1CA2CA7CA9
	SCHEMBL1458210	0.82	ALDH1A1 (0.54)	KDM4EGAARORCALDH1A1MAPT
	SCHEMBL5232828	0.82	CYP3A4 (0.47)	CA12CA1CA2CA7CA9
	SCHEMBL1457837	0.82	CA12 (0.46)	CA12CA1CA2CA7CA9
	SCHEMBL1458314	0.81	KMT2A (0.48)	CA12CA1CA2CA7CA9
	SCHEMBL9576403	0.81	XDH (0.67)	CA12CA1CA2CA7CA9
	SCHEMBL1457744	0.81	MAPT (0.61)	LMNAGFERALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.