Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 15/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.69 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.66 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161267 | 1.00 | PYGL (1.00) | PYGLEGFRCYP51A1CTNNB1 | |
| SCHEMBL29360910 | 0.94 | PYGL (0.88) | PYGLEGFRCYP51A1CTNNB1 | |
| Phenylalanine Methyl Ester SCHEMBL9051782 | 0.93 | PYGL (0.87) | PYGLEGFRCYP51A1CTNNB1 | |
| SCHEMBL6162920 | 0.92 | PYGL (0.85) | PYGLEGFRCYP51A1 | |
| SCHEMBL6162905 | 0.91 | PYGL (0.83) | PYGLEGFRCYP51A1 | |
| SCHEMBL6162901 | 0.91 | PYGL (0.83) | PYGLEGFRCYP51A1 | |
| SCHEMBL29358053 | 0.90 | PYGL (0.81) | PYGLCTNNB1 | |
| SCHEMBL6339472 | 0.90 | PYGL (0.81) | PYGLEGFRCTNNB1 | |
| SCHEMBL6165218 | 0.90 | PYGL (0.81) | PYGLEGFRCYP51A1CTNNB1 | |
| SCHEMBL6165213 | 0.90 | PYGL (0.81) | PYGLEGFRCYP51A1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | PYGL 1/4885EGFR 4538/4885CYP51A1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.