Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | SI | P14410 | 6/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.45 |
| ▸ | PARP1 | P09874 | 9/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717701 | 0.81 | MGAM (0.48) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL4716304 | 0.80 | GAA (0.47) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL4715176 | 0.79 | MGAM (0.43) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL4712950 | 0.76 | ALDH1A1 (0.44) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL4717461 | 0.76 | MGAM (0.43) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL27961298 | 0.74 | ADORA1 (0.57) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL4715207 | 0.73 | GAA (0.54) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL5666118 | 0.72 | PARP1 (0.43) | ADORA3ADORA1MGAMGAASI | |
| SCHEMBL15330385 | 0.72 | NPY5R (0.50) | PTGES | |
| SCHEMBL15330826 | 0.72 | HPGDS (0.54) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | ADORA3 726/4885ADORA1 246/4885MGAM 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.