Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587801 | 0.84 | GPBAR1 (0.33) | CYP2C19 | |
| SCHEMBL5012083 | 0.82 | PRSS12 (0.31) | CYP2C19 | |
| SCHEMBL14587800 | 0.77 | CYP2C19 (0.37) | CYP2C19 | |
| SCHEMBL27706777 | 0.76 | PYGL (0.37) | — | |
| Hydrochloric Acid SCHEMBL5008273 | 0.76 | CYP2C19 (0.37) | CYP2C19 | |
| SCHEMBL5010641 | 0.74 | PYGL (0.37) | CYP2C19 | |
| SCHEMBL5013485 | 0.74 | CYP2C19 (0.36) | CYP2C19 | |
| SCHEMBL5009797 | 0.74 | NPC1 (0.44) | CYP2C19 | |
| SCHEMBL14297710 | 0.73 | CYP2C19 (0.41) | CYP2C19 | |
| SCHEMBL5009741 | 0.73 | CYP2C19 (0.36) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | CYP2C19 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.