Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975480 | 0.81 | EPHX1 (0.79) | GAAEPHX1CCR3ALDH1A1EPHX2 | |
| SCHEMBL491868 | 0.81 | EPHX1 (0.79) | GAAEPHX1CCR3ALDH1A1EPHX2 | |
| SCHEMBL17525451 | 0.81 | HRH3 (0.46) | TP53TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL491685 | 0.80 | FPR3 (0.49) | GAAEPHX1RAD52TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL6337391 | 0.79 | RAD52 (0.49) | GAAEPHX1RAD52TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL6347355 | 0.79 | FPR3 (0.48) | GAAEPHX1RAD52TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL6340260 | 0.79 | SIGMAR1 (0.48) | GAAEPHX1RAD52TP53CYP1A2 | |
| SCHEMBL2905190 | 0.77 | ALDH1A1 (0.44) | RAD52CYP1A2TSHRSIGMAR1SMN1; SMN2 | |
| Iodide SCHEMBL4010788 | 0.76 | ALDH1A1 (0.43) | RAD52CYP1A2TSHRSIGMAR1SMN1; SMN2 | |
| SCHEMBL1827421 | 0.76 | EPHX1 (0.66) | EPHX1SIGMAR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169928-B2 | central nervous system disorders; Alzheimer's disease; attention deficit disorders; cognition activators; psychological disorders; antidepressants | SOCIETE CIVILE BIOPROJECT (FR) | 2007-01-30 | — | — | US | disclosed |
| US-7169928-B2 | central nervous system disorders; Alzheimer's disease; attention deficit disorders; cognition activators; psychological disorders; antidepressants | SOCIETE CIVILE BIOPROJECT (FR) | 2007-01-30 | — | — | US | disclosed |