Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | CCR3 | P51677 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491868 | 1.00 | EPHX1 (0.79) | EPHX1GAACCR3EPHX2KDM4E | |
| SCHEMBL12196118 | 0.88 | EPHX1 (1.00) | EPHX1GAACCR3EPHX2ALDH1A1 | |
| SCHEMBL3896010 | 0.83 | EPHX1 (0.54) | EPHX1GAAKDM4EALDH1A1 | |
| SCHEMBL9750349 | 0.81 | EPHX1 (0.86) | EPHX1EPHX2KDM4EALDH1A1 | |
| SCHEMBL19420509 | 0.81 | EPHX1 (0.86) | EPHX1EPHX2KDM4EALDH1A1 | |
| SCHEMBL14592001 | 0.81 | GAA (0.55) | EPHX1GAACCR3EPHX2ALDH1A1 | |
| SCHEMBL17525452 | 0.81 | KDM4E (0.54) | EPHX1GAAKDM4E | |
| SCHEMBL10642292 | 0.81 | EPHX1 (0.66) | EPHX1GAACCR3EPHX2ALDH1A1 | |
| SCHEMBL10642211 | 0.81 | EPHX1 (0.62) | EPHX1GAACCR3 | |
| SCHEMBL7522076 | 0.80 | ALDH1A1 (0.56) | EPHX1GAACCR3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815951-B2 | Inhibitors of epoxide hydrolases for the treatment of inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |