Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471042 | 0.82 | HSD11B1 (0.45) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL14627468 | 0.81 | ALDH1A1 (0.41) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12092350 | 0.78 | HSD11B1 (0.45) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10254140 | 0.78 | BLM (0.43) | HSD11B1ALDH1A1MEN1KMT2ATACR1 | |
| SCHEMBL23471247 | 0.78 | L3MBTL1 (0.61) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL14595357 | 0.77 | HSD11B1 (0.41) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12092346 | 0.77 | HSD11B1 (0.41) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL19634489 | 0.76 | GNAI3 (0.59) | HSD11B1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL21015511 | 0.76 | ATM (0.42) | HSD11B1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL17943670 | 0.74 | ALDH1A1 (0.39) | HSD11B1ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015766-A1 | Quinoline Derivatives as NK-3 and NK-2 Antagonists | GlaxoSmithKline S.P.A. & Laboratoire | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015766-A1 | Quinoline Derivatives as NK-3 and NK-2 Antagonists | KCNK3, KCNQ3, ACKR3 | HSD11B1 2234/4885ALDH1A1 3182/4885MEN1 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.