Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268416 | 0.85 | PKM (0.60) | THRBPOLBMAPTPKMELANE | |
| SCHEMBL689560 | 0.83 | TDP1 (0.52) | THRBTGM2POLBMAPTPKM | |
| SCHEMBL27403594 | 0.82 | THRB (0.46) | THRBTGM2POLBMAPTPKM | |
| SCHEMBL2587522 | 0.82 | THRB (0.64) | THRBTGM2MAPTPKMELANE | |
| SCHEMBL964748 | 0.81 | CA2 (0.54) | THRB | |
| SCHEMBL11346616 | 0.81 | TDP1 (0.50) | THRBTGM2POLBMAPTPKM | |
| SCHEMBL11205293 | 0.81 | THRB (0.49) | THRBTGM2POLBMAPTPKM | |
| SCHEMBL1373940 | 0.81 | THRB (0.49) | THRBTGM2POLBMAPTPKM | |
| SCHEMBL9568741 | 0.81 | SMN1; SMN2 (0.58) | THRBPOLBMAPTPKMELANE | |
| SCHEMBL8784007 | 0.80 | THRB (0.41) | THRBTGM2PTGS2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124203-A | Chemical compounds | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | CN | disclosed |
| US-7186489-B2 | Electrophotographic photosensitive member, electrophotographic photosensitive member manufacturing process, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2007-03-06 | — | — | US | disclosed |