⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878239 | 0.69 | — | — | |
| SCHEMBL15492133 | 0.57 | ADRA2C (0.36) | — | |
| SCHEMBL1321551 | 0.57 | ABL1 (0.35) | — | |
| SCHEMBL31006320 | 0.55 | — | — | |
| SCHEMBL31563006 | 0.53 | ENO1 (0.31) | — | |
| SCHEMBL22733469 | 0.50 | IDUA (0.31) | — | |
| SCHEMBL10746362 | 0.48 | — | — | |
| SCHEMBL22733471 | 0.48 | IDUA (0.35) | — | |
| SCHEMBL16241627 | 0.48 | ADRA2C (0.30) | — | |
| SCHEMBL7096091 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | US | disclosed |
| US-20070015757-A1 | Novel Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | US | disclosed |